Ovarian Malignancy : Routine Investigations & Specific Investigations :

Routine Investigations :
1.Hemogram , Blood group;
2.Liver function tests;
3.Kidney function tests;
4.Fasting and postprandial blood sugars;
5.Urine – routine/microscopy;
6.X-Ray chest (PA view);
7.ECG.

Specific Investigations:
1.Tumor markers
CA-125 >35 UI/l in epithelial tumors;
CEA
AFP – Increased in embryonal carcinoma and endodermal sinus tumor;
HCG – Increased in choriocarcinoma;
PLAP,LDH – Increased in dysgerminoma
Inhibin B – Increased in granulose cell tumor
2.USG and USG guided FNAC;
3.Contrast enhanced CT scan;
4.Intravenous pyelography (IVP);
5.Barium enema – To rule out carcinoma of colon;
6.Colonoscopy , upper GI endoscopy to rule out Krukemberg tumor ;
7.Cystoscopy if spread to bladder is suspected;
8.Endometrial biopsy , endocervical curettage –if history of postmenopausal bleeding or menstrual irregularities;
9.Ascitic fluid tap for biochemistry , cytology for confirmation of tissue diagnosis.